考虑黏结滑移效应对钢筋混凝土内力的影响

钢筋混凝土的黏结滑移性能会影响构件的受拉刚度,但是在工程设计中,忽略了考虑黏结滑移对钢筋混凝土内力的影响,这会对计算结果造成很大的误差.通过对两端固定连接的钢筋混凝土杆件在跨中区域的轴向力作用下的弹塑性性能进行研究,推导了考虑黏结滑移的内力计算公式,同时使用ANSYS软件模拟出未滑移阶段的黏结应力与钢筋应力的比例系数计算公式,并通过与实验结果的比较,验证了计算公式的准确性.通过算例对比分析发现,考虑黏结滑移和不考虑黏结滑移时算例的内力计算结果差异很大,最大内力误差将近80%左右,因此认为钢筋与混凝土黏结滑移的影响是不可忽略的.     

水平井在姬塬油田铁平7井区的应用效果研究

鄂尔多斯盆地伊陕斜坡西南部的铁平7井区油藏属于典型的底水发育的低渗透岩性—构造油藏,油藏具有油层厚度较薄,物性较差,单井产能较低的特点.通过对水平井与直井的应用效果分析对比后得出:水平井可以解决边底水突进过快的问题,并可增大泄油面积,提高单井产量,从而显著提高低渗透油藏产能,增加经济效益.     

不同放牧梯度上草原群落空间异质性的比较研究

以内蒙古呼伦贝尔草原为研究对象,利用幂函数法则定量地分析在轻度放牧、中度放牧和重度放牧3种不同利用方式下,群落的物种组成、物种多样性、群落空间异质性等群落特征。结果表明:随着放牧强度的增加,群落组成结构改变,群落丰富度逐渐降低,轻牧＞中牧＞重牧;不同放牧梯度上,各物种种群在实际分布上均具有较强的空间异质性,即偏离随机分布呈现集中分布趋势;不同放牧梯度上,群落总体空间异质性指数变化规律为轻牧=重牧＞中牧,均匀度指数的变化规律为中牧＞轻牧＞重牧。     

血清Ig类、BNP和D-二聚体检测与急性心肌梗死(AMI)的相关性研究

目的探讨急性心肌梗死(AMI)患者血清中IgA,IgG,IgM,BNP和D-二聚体(D-D)浓度的变化与AMI的关系.方法利用免疫比浊法和荧光免疫法对60例AMI患者血清中IgA,IgG,IgM,BNP和D-D浓度进行测定,并与30例正常对照组比较.结果AMI患者血清中的IgA,IgG,IgM,BNP和D-D浓度明显高于正常对照组,与疾病严重程度呈正相关.结论监测AMI患者血清IgA,IgG,IgM,BNP和D-D浓度的变化,对AMI严重程度评估和疗效观察有重要的临床意义.     

汽车自适应巡航控制的间距策略

汽车自适应巡航控制中,为确定不同车距下的控制策略,通过建立汽车行驶模型和制动模型,推导得到车速判据、第一车距判据、第二车距判据。将前后两车之间距离按此三条判据,由前至后划分为避撞区域、制动区域、降速区域、加速区域。自适应巡航系统能够判断和识别汽车当前所处区域,能够决定当前所应采取的驱动控制和制动控制策略。     

数据活跃度感知的延迟容忍网络数据转发机制

根据延迟容忍网络中的数据活跃程度与其扩散速度直接相关的规律,提出了数据活跃程度感知的延迟容忍网络数据转发机制.根据数据平均投递周期,节点以分布式方式衡量数据的活跃程度,并在此基础上预测数据期望投递跳数,进而控制数据复制转发的扩散程度.仿真结果表明该机制能够大幅度改善数据成功投递率和网络平均延迟.     

用数字化建库方法建立黄石市土地利用现状信息库

本文联系建立湖北省黄石市土地利用现状图数据库的生产实际,介绍了用数字化方法建立土地利用现状数据库的过程以及建库过程中在数据采集、数据转换、数据检查和质量控制等方面关键技术问题。     

Metformin targets liver tumor-initiating cells through the PI3K/Akt/mTOR survival pathway

Liver tumor-initiating cells （T-ICs） are thought to be inherently resistant to the cytotoxic effects of chemo- therapy, and can self-renewal and maintain tumor-initiating potential. Therefore, effective anticancer research strategies should target the unique properties of T-ICs. In this study, we found that metformin, a first-line drug of choice for the treatment of type 2 diabetes, inhibited liver T-ICs both in vivo and in vitro. Metformin inhibited the formation of hepato- spheres and epithelial-specific antigen-positive （ESA, CD133＋） cell colonies by hepatocellular carcinoma （HCC） cell lines. Metformin also downregulated the expression of several T-IC-related genes which are involved in the signal- ing pathways, governing the self-renewal, proliferation and differentiation of T-ICs. Furthermore, the targeting of liver T-ICs by metformin was PI-3-kinase-Akt-mTOR （PI3K/Akt/ mTOR）-pathway dependent. The PI3K/Akt/mTOR inhibitorLY294002 and rapamycin abolished the inhibitory effect of metformin on CD133＋ cells, and the PI3K/Akt/mTOR stimulator EGF promoted the inhibitory effect of mefformin on CD 133＋ cells. Metformin also dramatically decreased the tumor volume and number of CD133 expressing tumor cells in a xenograft mouse model. Mefformin exerted a synergistic effect with cisplatin to target both T-ICs and non-T-ICs, and resulted in the smallest tumor volume and lowest number of CD133 expressing tumor cells. This study indicates that the antidiabetic drug metformin could potentially be used in combination therapy with chemotherapeutic agents to improve the treatment of liver cancer.     

Transmission and demodulation of multi-polarization-multiplexed signals

We propose the configuration of signal multiplexing with four polarization states and investigate its transmission performance over single-mode fiber links. Using coherent detection and digital signal processing, a demodulation scheme for four-polarization-multiplexed (4PM) system is presented. We discuss the impact of crosstalk from polarization mode dispersion and polarization beam splitter misalignment on the proposed 4PM system. Furthermore, the transmission distance could be doubled to ~50 km by employing feedback decision equalizers.     

New secondary batteries and their key materials based on the concept of multi-electron reaction

Facing the significant applications in energy field, this paper introduces how to construct new high specific energy secondary batteries based on the concept multi-electron reaction and by designing multi-electron electrode materials. Recent progress on those new secondary batteries and their key materials based on the theory of multi-electron reaction are overviewed. Representative multi-electronic electrode materials, such as metal borides, metal fluorides, sulfur composite electrode materials and ferrates are briefly introduced, as well as the new secondary battery systems constructed with these materials. Thus gives the significance of the development based on multi- electron reaction mechanism of secondary batteries and their key materials for new chemical battery systems and related energy materials.